At Illinois

  • [50] J. Sickle, C. Ni, D. Shen, D. Zhang, M. Jin, and T. Lu
    Integrative circuit-host modeling of a genetic switch in varying environments
    Scientific Reports, 10: 8383 (2020)
  • [49] X. Huang, Y. Fan, T. Lu, J. Kang, X. Pang, B. Han, and J. Chen
    Composition and metabolic functions of the microbiome in fermented grain during light-flavor Baijiu fermentation
    Microorganisms, 8: 1281 (2020)
  • [48] F. Liu, J. Mao, T. Lu* and Q. Hua* (*Co-corresponding authors)
    Synthetic, context-dependent microbial consortium of predator and prey
    ACS Synthetic Biology 8: 1713-1722 (2019)
  • [47] F. Liu, J. Mao, W. Kong, Y. Feng, Q. Hua, R. Bashir, and T. Lu
    Interaction variability shapes succession of synthetic microbial ecosystems
    Nature Communications, doi: 10.1038/s41467-019-13986-6 (2019)
  • [46] H. Cheng, D. Cheng, J. Mao, T. Lu, and P. Hong
    Identification and characterization of core sludge and biofilm microbiota in anaerobic membrane bioreactors
    Environmental International 133: 105165 (2019)
  • [45] X. Fang, K. Kruse, T. Lu, and J. Wang
    Nonequilibrium physics in biology
    Review of Modern Physics 91: 045004 (2019)
  • [44] V. Celik, W. Kong, A. Blanchard, F. Liu, and T. Lu
    Spatial interference scale as a determinant of microbial range expansion
    Science Advances 4: eaau0695 (2018).
  • [43] M. A. Khatun, M. A. Hoque, Y. Zhang, T. Lu, L. Cui, N. Zhou, and Y. Feng
    Bacterial consortium-based sensing system for detecting organophosphorus pesticides
    Analytical Chemistry 90 (17): 10577-10584 (2018).
  • [42] Q. Tang, T. Lu*, and S. Liu* (*Co-corresponding authors)
    Developing a synthetic biology toolkit for comamonas testosteroni, an emerging cellular chassis for bioremediation
    ACS Synthetic Biology 7: 1753-1762 (2018).
  • [41] W. Kong, D. Meldgin, J. Collins, and T. Lu
    Designing microbial consortia with defined social interactions
    Nature Chemical Biology 14: 821–829 (2018).
  • [40] Q. Tang, T. Lu*, and S. Liu* (*Co-corresponding authors)
    Engineering the bacterium comamonas testosteroni CNB-1: plasmid curing and genetic manipulation
    Biochemical Engineering Journal 133: 74-82 (2018).
  • [39] Z. Zhang, P. Jiménez-Bonilla, S. Seo, T. Lu, Y. Jin, H. Blaschek, and Y. Wang
    Bacterial genome editing with CRISPR-Cas9: taking clostridium beijerinckii as an example
    In Synthetic Biology, Methods in Molecular Biology (Jeff Braman, et al. eds), 1772: 297-325 (2018).
  • [38] T. Lu
    Principles of Systems Biology, No. 23
    Cell Systems 5: 428 (2017).
  • [37] A. Blanchard, C. Liao, and T. Lu
    Circuit-host coupling induces multifaceted behavioral modulations of a gene switch
    Biophysical Journal 114: 1-10 (2017).
  • [36] S. Seo, T. Lu, Y. Jin and H. Blaschek
    Development of an oxygen-independent flavin mononucleotide-based fluorescent reporter system in clostridium beijerinckii and its applications
    Journal of Biotechnology 265: 119-126 (2017)
  • [35] C. Liao, A. Blanchard, and T. Lu
    An integrative circuit-host modeling framework for predicting synthetic gene network behaviors
    Nature Microbiology 2: 1658–1666 (2017).
  • [34] T. Lu
    What is the role of circuit design in the advancement of synthetic biology?
    Cell Systems 4: 476 (2017)
  • [33] S. Seo, H. Janssena, A. Magise, Y. Wang, T. Lu, N. Price, Y. Jin, and H. Blaschek
    Genomic, transcriptional and phenotypic analysis of the acid-crash mutant of clostridium beijerinckii
    Biotechnological Journal 12: 1700182 (2017)
  • [32] W. Kong, A. Blanchard, C. Liao, and T. Lu
    Engineering robust and tunable spatial structures with synthetic gene circuits
    Nucleic Acids Research 45: 1005-1014 (2016)
  • [31] A. Blanchard, C. Liao, and T. Lu
    An ecological understanding of quorum sensing-controlled bacteriocin production
    Cellular and Molecular Bioengineering 9: 443-454 (2016)
  • [30] S. Seo, Y. Wang, T. Lu, Y. Jin, and H. Blaschek
    Characterization of a clostridium beijerinckii spo0A mutant and its application for butyl butyrate production
    Biotechnology and Bioengineering 114: 106-112 (2016)
  • [29] C. Liao, S. Seo, and T. Lu
    System-level modeling of acetone-butanol-ethanol fermentation
    FEMS Microbiology Letter 363: fnw074 (2016)
  • [28] Y. Wang, Z. Zhang, S. Seo, P. Lynn, T. Lu, Y. Jin, and H. Blaschek
    Gene transcription repression in clostridium beijerinckii using CRISPR-dCas9
    Biotechnology and Bioengineering 113: 2739-2743 (2016)
  • [27] Y. Wang, Z. Zhang, S. Seo, P. Lynn, T. Lu, Y. Jin, and H. Blaschek
    Bacterial genome editing with CRISPR/Cas9: deletion, integration, single nucleotide modification, and desirable ‘clean’ mutant selection in clostridium beijerinckii as an example
    ACS Synthetic Biology 5: 721–732 (2016)
  • [26] T. Lu
    Piecing together the puzzle of solvent production
    Biofuels International 10: 41-42 (2016)
  • [25] J. Mao and T. Lu
    Population-dynamic modeling of bacterial horizontal gene transfer by natural transformation
    Biophysical Journal 110: 258–268 (2015)
  • [24] W. Kong, V. Kapuganti, and T. Lu
    A gene network engineering platform for lactic acid bacteria
    Nucleic Acid Research 44(4): e37 (2015)
  • [23] A. Blanchard and T. Lu
    Bacterial social interactions drive the emergence of differential spatial colony structures
    BMC Systems Biology 9: 59 (2015)
  • [22] C. Liao, S. Seo, V. Celik, H. Liu, W. Kong, Y. Wang, H. Blaschek, Y. Jin, and T. Lu
    Integrated, systems metabolic picture of acetone-butanol-ethanol fermentation by clostridium acetobutylicum
    Proc. Natl. Acad. Sci. 112: 8505–8510 (2015)
  • [21] Y. Wang, Z. Zhang, S. Seo, K. Choia, T. Lu, Y. Jin, and H. Blaschek
    Markerless chromosomal gene deletion in clostridium beijerinckii using CRISPR/Cas9 system
    Journal of Biotechnology 200: 1-5 (2015)
  • [20] H. Liu and T. Lu
    Autonomous production of 1,4-butanediol via a de novo biosynthesis pathway in engineered escherichia coli
    Metabolic Engineering 29: 135-141 (2014)
  • [19] W. Kong, V. Celik, C. Liao, Q. Hua, and T. Lu
    Programming the group behaviors of bacterial communities with synthetic cellular communication
    Bioresources and Bioprocessing 1:24 (2014)
  • [18] H. Liu, Y. Wang, Q. Tang, W. Kong, W. Chung, and T. Lu
    MEP pathway-mediated isopentenol production in metabolically engineered escherichia coli
    Microbial Cell Factory 13:135 (2014)
  • [17] W. Kong and T. Lu
    Cloning and optimization of a nisin biosynthesis pathway for bacteriocin harvest
    ACS Synthetic Biology 3: 439-45 (2014)
  • [16] A. Blanchard, V. Celik, and T. Lu
    Extinction, coexistence, and localized patterns of a bacterial population
    BMC Systems Biology 8:23 (2014)
  • [15] J. Mao, A. Blanchard, and T. Lu
    Slow and steady wins the race: A bacterial exploitative competition strategy in fluctuating environments
    ACS Synthetic Biology 4: 240–248 (2014)
  • [14] C. Liao and T. Lu
    A minimal transcriptional controlling network of regulatory T cell development
    Journal of Physical Chemistry B 117: 12995–13004 (2013)
  • [13] H. Qi, A. Blanchard, and T. Lu
    Engineered genetic information processing circuits
    WIREs Systems Biology and Medicine 5: 273–287 (2013)
  • [12] W. Fu, T. Lu*, A. Ergun*, J. Hill, S. Haxhinasto, M. Fassett, R. Gazit, S. Adoro, S. Chan, D. Rossi, J. Collins, D. Mathis, and C. Benoist
    A multiply redundant genetic switch 'locks in' the transcriptional signature of Treg cells
    Nature Immunology 13: 972-980 (2012) (*Equal contribution)

Prior to joining Illinois

  • [11] D. Karig, K. Martini, T. Lu, N. DeLateur, N. Goldenfeld, and R. Weiss
    Stochastic Turing patterns in a synthetic bacterial population
    Proc. Natl. Acad. Sci. 115: 6572-6577 (2018)
  • [10] W. Ruder*, T. Lu*, and J. J. Collins
    Synthetic biology moving into the clinic
    Science 333: 1248-1252 (2011) (*Equal contribution)
  • [9] J. Beal, T. Lu, and R. Weiss
    Automatic compilation from high-level language to genetic regulatory networks
    PLoS One 6: e22490 (2011)
  • [8] C. Teuscher, C. Grecu, T. Lu, and R. Weiss
    Challenges and promises of nano and bio communication networks
    Proc. ACM/IEEE Fifth Int’l Symp. Networks-on-Chip, pp. 247-254 (2011)
  • [7] T. Lu, M. Ferry, R. Weiss, and J. Hasty
    A molecular noise generator
    Physical Biology 5: 036006 (2008)
  • [6] T. Lu, T. Shen, M. Bennett, P. Wolynes, and J. Hasty
    Phenotypic variability of growing cellular populations
    Proc. Natl. Acad. Sci. 104: 18982-18987 (2007)
  • [5] T. Lu, J. Hasty, and P. Wolynes
    Effective temperature in stochastic kinetics and gene networks
    Biophysical Journal 91: 84-94 (2006)
  • [4] T. Lu, T. Shen, C. Zong, J. Hasty, and P. Wolynes
    Statistics of cellular signal transduction as a race to the nucleus by multiple random walkers in compartment/phosphorylation space
    Proc. Natl. Acad. Sci. 103: 16752-16757 (2006)
  • [3] C. Zong, T. Lu, T. Shen, and P. Wolynes
    Nonequilibrium self-assembly of linear fibers: microscopic treatment of growth, decay, catastrophe and rescue
    Physical Biology 3: 83-92 (2006)
  • [2] T. Lu, D. Volfson, L. Tsimring and J. Hasty
    Cellular growth and division in the Gillespie algorithm
    IET Systems Biology 1:121-127 (2004)
  • [1] T. Lu and Y. Li
    Mesoscopic circuit with linear dissipation
    Modern Physics Letter B, 16: 975-979 (2002)